On December 23rd, CCTV’s "Dialogue" column took the power of industry as the theme, and invited five representatives of enterprises that won the "China Industry Award" to talk with academicians and experts about the "lack of core and soul" and "the pain of locking the throat" of China’s industry and the "rickets" made in China. Hao Xiaofeng, president of Kanghong Pharmaceutical, participated in the program as an invited guest. On December 9th, Kanghong Pharmaceutical won the "China Industry Award" in the 5th China Industry Award for the project of "Development of the National First Class New Drug Compaxip Eye Injection".
Hao Xiaofeng, president of Kanghong Pharmaceutical, talks about the scene of Dialogue.
At the scene of the program, Mr. Hao shared: Compaq Sip is the only innovative medicine in this year’s industrial award-winning project, and many friends call it "Tiny" very affectionately. Its capacity is only 0.2 ml, which is only a drop of water. However, it took more than ten years to innovate and produce it industrially, costing nearly 1 billion yuan. In daily storage and transportation, it must be kept at a constant temperature of 2 to 8 degrees Celsius. Many friends have heard of cataract and glaucoma, but many friends are not familiar with macular degeneration, which is one of the three major blinding diseases in the world. There are more than 4 million patients with macular degeneration in China. If the patients are not treated effectively, they will live in darkness forever. Today, with this drop of water, more than 500,000 patients with macular degeneration in China have been treated more safely and effectively, and at the same time, the treatment cost has been reduced by two thirds, saving nearly 10 billion yuan in the medical cost of the whole society.
Hao Xiaofeng talks about the innovative power of "a drop of water"
Compaq Xipu Eye Injection, an award-winning product of the 5th China Industrial Awards.
How to change the helplessness in Dying to Survive?
When it comes to the pain of throat lock, Mr. Hao said that there will be many vivid faces that reveal helplessness, desolation and even misery. In the past, there was no cure for age-related macular degeneration, and only blindness was waiting for patients, which was a kind of helplessness. Until 2006, there were effective drugs to treat this disease in the world, but the price was too high for most patients to afford. As shown in Dying to Survive, it is a kind of desolation and misery for patients to go from hope to disappointment. After the emergence of Compaxip, it provided patients with a better curative effect, less injection frequency and lower economy, which enabled many patients with financial difficulties to get timely treatment and restore their sight. At the same time, with Compaxip’s entry into the national medical insurance and the national basic drug list, it will further reduce the burden on patients and improve the medical efficiency of society.
Will the concept that domestic production is inferior to import change?
Mr. Hao shared: When Compaq Xipu was first listed, doctors often asked patients, there are two drugs, one is imported, which is more expensive, and the other is made in China, which is cheaper. Do you use imported or made in China? As pharmaceutical companies, we should try our best to change this situation. The future is like this. Doctors ask patients that there are two drugs, one is expensive, imported and the other is cheap, exported.
In September 2016, Compaq Sip was approved by the FDA of the United States, becoming the first innovative drug in China to directly carry out phase III clinical research in the United States. It is conducting clinical research in nearly 50 countries and more than 300 hospitals around the world, and will soon enter the global market and contribute to the "China Program".
How to ensure the effectiveness of each drug?
The inspection of drugs is a destructive inspection, which is one-off. Therefore, any piece of medicine that enters the market, any medicine is untested. However, to ensure that it is qualified, all pharmaceutical companies must do GMP certification, and a concept of "batch" will be introduced. Any instruction can not flow to the next batch, completely separated, and a large number of experiments are used to prove that it is uniform in space and stable in time.
Compaq Xipu production base meeting international standards
Why is research and development of new drugs a road of no return?
Mr. Hao sighed with emotion: drug innovation is a small probability event. From research and development to industrial production, drugs are a road that cannot be turned back. No one can guarantee whether the huge investment in the early stage will be successful. The failure of one link will often lead to the abandonment of the whole project, and the efforts that have been struggling for more than ten years or even longer will be wasted.
Kang Hong feels very lucky to stand on the stage of Dialogue. On the road of medical innovation, many colleagues have endured great pressure for ten years and devoted themselves to research and development. Although few have succeeded, they are still persisting. It is the initial intention of pharmaceutical people to be "clinical demand-oriented" that supports them to face failure and forge ahead bravely. Therefore, he hopes that the public can give more tolerance and time to pharmaceutical people and give more confidence and strength to China’s pharmaceutical industry!
At the end of the program, on behalf of Kanghong Pharmaceutical, Mr. Hao promised the national audience: "I am willing to develop more world-class innovative drugs as a part of China pharmaceutical industry."
In view of the spiritual outlook of a person and an institution in the field of medical and health care in this article, the health sector recommends them to participate in the "Honor to the Power of Climbing-Annual Influence Selection of Health Sector (2018-2019)", and immediately [click here] or scan the QR code below to vote for them and pay tribute to the climbers!
[car home Yantai Preferential Promotion Channel] Recently, we learned from the dealers that preferential activities are being carried out, with the maximum discount range of 20,000 yuan and the minimum starting price of 132,800 yuan. If you are interested in this model, please click "Check the car price" in the quotation form to get a higher discount.
The exterior design of Starway Eta Ursae Majoris adopts an avant-garde style, and the front part is equipped with an integrated air intake grille and slender LED headlight group, which makes the whole vehicle look very powerful. The overall body lines are smooth and full of sports.
Starway Eta Ursae Majoris has a length, width and height of 4781*1920*1671mm and a wheelbase of 2815mm, showing a broad and elegant body proportion. Its side lines are smooth and dynamic, and with the precise design of the front wheel track of 1641mm and the rear wheel track of 1642mm, the stability and handling of the vehicle are ensured. In terms of tires, 245/50 R20 specifications are adopted at the front and rear, with exquisite rim style, which further enhances the fashion sense and sporty atmosphere of the whole vehicle.
The interior of Starway Eta Ursae Majoris adopts a simple and fashionable design style, with exquisite materials and details, creating a high-end comfortable driving experience. The steering wheel is made of genuine leather, with delicate feel. It supports manual adjustment up and down and back and forth to meet the individual needs of different drivers. The central control area is equipped with a 12.3-inch high-definition touch screen, which integrates various functions such as multimedia system, navigation, telephone and air conditioning, and supports voice recognition control, which is convenient and practical. The seat is also wrapped in leather. Both the main driver’s seat and the co-driver’s seat have multiple adjustment functions, including front and rear adjustment, backrest adjustment, height adjustment and leg rest adjustment. At the same time, it is equipped with electric seat memory function, which further improves the riding comfort. The main driver’s seat also has massage, heating and ventilation functions, providing a comfortable experience for long-distance driving. The second row of seats supports backrest adjustment and proportional reclining, providing flexible spatial layout and comfortable riding experience. In addition, the car is also equipped with multiple USB and Type-C interfaces and wireless charging function of mobile phones, which meets the needs of modern technology travel.
Starway Eta Ursae Majoris is equipped with a 2.0T engine with a maximum power of 192kW and a maximum torque of 400N·m, and adopts the L4 engine structure. Matching it is a 7-speed wet dual-clutch gearbox, which provides drivers with strong power output and smooth shifting experience.
The owner of car home said that the appearance design of Starway Eta Ursae Majoris was impressive, especially the black body was more textured after washing the car. He believes that the design of the side and back is particularly excellent, but the front face is slightly insufficient. Generally speaking, the appearance of Xingtu Eta Ursae Majoris has a unique charm, which is worth savoring.
In recent years, with the increasing number of electric vehicles, traffic safety and riding safety have attracted more and more attention from all walks of life. As a leader in the domestic intelligent two-wheeled electric vehicle industry, No.9 Company (689009·SH) has joined hands with all parties to advocate riding safety, build a user riding safety defense line with practical actions, and contribute to the long-term sustainable development of the industry.
On the one hand, internally, adhere to quality as the foundation. Relying on the advanced digital production control system, strict quality inspection process and comprehensive verification by CNAS National Laboratory, No.9 Company has formed a perfect quality management system, which can ensure that every factory product meets No.9′ s high quality standards.
At the same time, Company No.9 is also increasing its research and development efforts to improve the performance and quality of electric vehicles. According to the company’s semi-annual report, during the reporting period, the company’s R&D investment reached 349 million yuan, up 18.88% year-on-year, and the number of intellectual property rights accumulated worldwide reached 4,985. The technological innovation ability became the core component of the company’s new quality productivity. Behind this figure is the firm commitment of No.9 Company to improve product performance and quality.
Taking its Nz MIX electric vehicle as an example, Company No.9 has made great efforts in the structural safety of the whole vehicle. The car adopts lightweight carbon steel frame, and the main beam tube and head tube of the frame are thickened and thickened, which greatly improves the stability. In addition, the front and rear are equipped with large-size tires, which have stronger grip. In addition, the front disc and rear drum brake design and TCS traction control system provide multiple safety guarantees for users to ride.
On the other hand, externally, Company No.9 cooperated closely with fire departments and traffic control departments in Nanjing, Zhengzhou, Wuhan and other places. Through a series of activities, such as "Public Welfare Lecture on Electric Vehicle Safety Science Popularization", "Electric Bicycle Safety Science Popularization" and the release of "Manual on the Safe Use of Electric Bicycles", Company No.9 joined hands with all parties to popularize the safe use of electric vehicles and raise public awareness of fire safety and riding norms, laying a solid foundation for building a safe and harmonious travel environment.
With excellent product strength, persistent innovation and strong brand power, No.9 Company has been widely recognized by the market. Now, it has been ranked first in the sales volume of smart two-wheeled electric vehicles in China for two consecutive years, with stores in more than 1,000 cities and counties across the country, making it the preferred brand for new generation consumers to travel. In the future, Company No.9 will continue to proceed from high-quality development, drive product strength to continue to improve, actively fulfill corporate social responsibility, and satisfy people’s beautiful pursuit of convenient, safe and intelligent travel with more excellent products and services. (promotion)
With the opening of the price reduction boom in the automobile market, many car companies have joined the price involution. BYD, which took the lead, has successively launched the glory version of its models, not giving other car companies a chance to catch their breath. Chery Automobile couldn’t help it. Recently, it launched the Chery iCAR 03, with a total of six models. Compared with the previous pre-sale price, the price of the new car continued to be greatly reduced after it went on the market, and the price came to 109,800-169,800 yuan, which was specially prepared for young consumers and built the first car for young people.
From the appearance point of view, Chery iCAR 03 basically adopts a lot of tough line design, the front face is equipped with a closed air intake grille, and the LOGO and headlights are designed with "I", which has a good visual impact. Its lower enclosing shape is very tough, and it also uses a black color design. The whole front face is very three-dimensional, which seems to have good wildness and recognition.
Chery iCAR 03 is positioned as a compact SUV with a body size of 4406*1910*1715mm and a wheelbase of 2715mm. Its body is a square "box" shape, its roof is blackened, creating a floating effect, its body is designed with a slender and straight waistline, and the hidden door handle can also reduce some wind resistance coefficient. In addition, its wheel arch adopts a convex shape, which looks very tough, and the off-road SUV is very full. Its tail shape is also highly recognizable. The taillights also use the "I" design, and the tailgate is also equipped with a square "small schoolbag". The shape surrounded by it is also very rough. The appearance of the whole city off-road SUV is quite popular with young people.
Its interior design is also very interesting. The car is equipped with a 9.2-inch full LCD instrument panel and a 15.6-inch suspended central control panel. The steering wheel is a flat-bottomed three-spoke multi-function steering wheel, and the sense of technology is still excellent. In addition, in the armrest box area, two thick handles are designed, which is also very hard-core. Although the price of the new car is reduced, the interior materials of the lowest model are not cut corners, and both the texture and workmanship are delicate.
In terms of power, Chery iCAR 03 provides two powertrains: two-wheel drive version and four-wheel drive version. The two-wheel drive version is equipped with a motor with a maximum power of 135kW, and the four-wheel drive version is equipped with a dual motor with a total maximum power of 205kW, and is equipped with an iWD intelligent electric four-wheel drive system. In terms of battery life, Chery iCAR 03 provides lithium iron phosphate batteries with capacities of 50.63kWh, 65.69kWh and 69.77kWh respectively, and the cruising range of CLTC is 401 km, 472 km and 501 km.
Conclusion: The appearance of Chery iCAR 03 is very hard and rough, and the overall style is mainly off-road. Its interior texture is also excellent. The shortcoming is that the space is not large, but it is ok at this price. However, friends who really want to go off-road should think more about it, because the new car is not a real off-road model, mainly based on urban travel and light off-road.
From the modeling point of view, L has adopted the family-style design language, which is a matter of opinion, but from the feedback of friends around me, it is really popular. Audi A8L’s hexagonal middle net is huge, and with the "Audi" logo, the outline of the front of the vehicle looks sharp and atmospheric, and the lights on both sides are quite beautiful, which makes it look very energetic after lighting up. The side of the car body is still Audi’s unique design style, and the enchanting figure is even more vivid! In addition, it makes its sports atmosphere more intense. At the same time, the tail of Founder’s vehicle echoes the front, and the penetrating taillights of LED light sources also have a certain sense of advanced.
Audi A8L puts the details into practice and extends the high quality from the appearance to the inside of the car. The large leather coverage of the steering wheel brings a good sense of luxury, and at the same time, it is practical with shift paddles. The whole center console is made of plastic, leather and wood, and the materials and workmanship look quite satisfactory. It is equipped with a 10.1-inch touch LCD screen, which is clear in display and natural in design. The front row is also equipped with a dual-temperature automatic air conditioning control system to freely debug the most comfortable space atmosphere. The self-adjusting seat is relatively comfortable and can hold the family firmly.
Audi A8 has a car length of 5450mm, a car body width of 1945mm and a wheelbase of 3258mm, which is quite satisfactory. In the same class, the wheelbase of Audi A8 ranks seventh. The interior space of the car is relatively spacious at the same level, the height and width of the car are ideal, and the legroom in the back row will not feel cramped, which belongs to the upper-middle level at the same level. The design of skylight also increases the subjective space feeling of front and rear passengers. Audi A8′ s trunk volume ranks 6th among the same price and class models. The space is relatively regular, without obvious protrusions, and the overall loading capacity is good.
Audi A8 is equipped with a 4.0 engine with a maximum output of 338kW and a maximum torque of 660Nm. It will definitely bring unforgettable control charm. The official measured acceleration of Audi A8 is 4.8S, ranking 16th among more than 800,000 car models.
The active/passive safety configuration of Audi A8 is complete, includingAutomatic parking、Zero tire pressure endurance tire、Automatic parking、Steep slope descent、hill start assist control、knee airbag、HUD head-up display、Anti-lock braking (ABS)、Braking force distribution (EBD/CBC, etc.)、Brake assist (EBA/BAS, etc.)、Traction control (ASR/TCS, etc.)、Active noise reduction、Engine start and stop、Side safety air curtain、Wireless charging of mobile phone、night vision system、LED daytime running lights、Forward reversing radar、Tire pressure monitoring、Steering wheel heating、Body stability control (ESP/DSC, etc.)、Rear reversing radar、Fatigue reminder、Remote parking、Child seat interface、Lane keeping (LKAS)Equal configuration.
Among them,Automatic parkingYou can avoid stepping on the brakes for a long time or needing to pull frequently;Steep slope descentCan safely pass through steep slope road conditions at low speed;knee airbagReduce the injury of the car interior to the occupant’s knees in the secondary collision.
In addition to the above description, we can also go to the Easy Car Forum to browse more real car feedback from actual buyers, or use our experience.
The cold test includes many aspects such as the exterior, interior, driving state and working condition of the vehicle, but the most intuitive aspects for users are cold start, defrosting, defogging, interior heating and driving experience.
Let’s talk about cold start first. First, the vehicle should stand outdoors for more than 12 hours at the lowest temperature of -30 to -35 degrees Celsius. According to the testers, the test process is fixed, and they have to adjust their work and rest time according to the temperature change, usually starting work at 5-7 am. Because this time period is the coldest, it meets the test requirements. Now Mohe is just dawn at about 8 am.
In the cold start project, there are two dimensions to measure the results. The first is the start-up time (within 10 seconds, it is up to standard), and the second is whether it can be successfully started at one time. After both of them meet the standards, only one set of tests has been completed, and only three sets have to be completed continuously to be qualified. It is reported that there is no problem. In the case of -35 degrees Celsius, the startup time is about 4 seconds.
For users in cold areas, the speed of vehicle defrosting and defogging is also very important. There are also two aspects to measure this project, namely, the time spent on defrosting and defogging and the corresponding area. Testers will collect and record data for these two aspects one by one. In addition, a comprehensive evaluation should be made based on the subjective feelings of drivers and passengers.
In addition to defrosting and defogging, the effect of air conditioning will be verified, and the tester will record the temperature of the air outlet and the temperature near the headrest. They also said that, for example, the lower air outlet of the foot should have the same air outlet, and one foot should not be cold and the other foot should be hot. It is reported that in the weather like Mohe, the water temperature of the engine can rise to about 70 degrees in about 5-6 minutes when the vehicle is idling after starting, and warm air is blown out at the air outlet.
Whether electronic components can work normally in low temperature environment is also the focus of staff testing. Auchan comes standard with an instrument panel with LCD screen, which is rare in the same model. As shown on the screen, the current outdoor temperature is -18 degrees Celsius, and the instrument information is all normal. The staff introduced that in the case of -30 degrees Celsius, when the vehicle just started and the water temperature was low, there would be a slight smear phenomenon when the big numbers on the dashboard changed, but this situation did not exist after the water temperature rose. There is no such situation on the screen of the sound system next to it. It can be displayed normally at any time, and the system responds quickly.
Road verification is also an indispensable part of every day, and the staff will drive vehicles to crawl at low speed and test urban roads, national highways and highways every day. On the way, acceleration and braking tests will be carried out according to road conditions to simulate normal driving habits. The speed range covers 0-120km/h, and the temperature ranges from 0 to -35 degrees Celsius. And according to the temperature change of 5 degrees Celsius as a calibration to collect data. At the same time, it is necessary to analyze the driver’s own subjective feelings to find out the potential problems that may exist in the vehicle.
● Summary:
The "three highs" test is mainly aimed at verifying the reliability of products, and Auchan has withstood the test in these aspects. It is not difficult to see from the "three highs" test learned this time that vehicle engineers are engaged in the same boring work day after day because of their fixed workflow and specifications and harsh environment. And all this is to truly simulate the car use of local users and ensure that vehicles can be used normally in any state. As the saying goes, it takes a lot of tempering to become steel.
The process and specifications of the "Three High" test involve the business secrets of the manufacturers, especially the data information, so they naturally don’t want to disclose it to me as an outsider. Secondly, the time for participation is very tight, and the information that can be learned is limited. Therefore, this article can only be written from the perspective of personal feelings. However, Auchan is about to be officially listed, and these boring experiments may not be as attractive as the test drive. As for Auchan’s performance in power and control, we will present you with wonderful test drive articles at the end of the month. (Text/Photo/Photo by Liu Wei)
In 2015, the bright spots of Internet development in China appeared frequently. This aspect benefited from the rich accumulation of talents, users, products, companies, capital and concepts after 20 years of development of the Internet in China, which ushered in a period of rapid development from a network power to a network power; On the other hand, thanks to the top-level design of the country and the active participation of the whole society, the "internet plus" has risen to the national strategic level, promoting mass entrepreneurship and innovation, and the Internet has become an indispensable part of China’s infrastructure construction, scientific and technological progress, economic transformation, social development, national governance and even international exchanges and cooperation.
Highlights of Internet Development in China in 2015
The 13th Five-Year Plan proposal adopted by the Fifth Plenary Session of the 18th CPC Central Committee emphasizes the implementation of the strategy of strengthening the country through network, the implementation of the "internet plus" action plan, the development of sharing economy and the implementation of the national big data strategy. The national top-level design has greatly promoted the Internet to penetrate all aspects of China’s economic, social and cultural development.
(A) the national strategic level
1. "internet plus" has risen to a national strategy and built a new ecology of economic development.
In March, the government work report proposed to formulate the "internet plus" action plan, and in June, the the State Council executive meeting adopted the "internet plus Action Guiding Opinions". In 2015, eight ministries and bureaus, including the National Development and Reform Commission, the Ministry of Industry and Information Technology, the Ministry of Communications, the Ministry of Agriculture, the Ministry of Commerce, the Health Planning Commission, the Tourism Bureau and the Energy Bureau, issued the "internet plus", among which the Ministry of Commerce has issued the first ministerial-level action plan, and the Ministry of Industry and Information Technology issued the "internet plus" three-year action plan. Subsequently, local versions of action plans were launched one after another. Fujian, Jiangxi, Jiangsu, Guangdong, Sichuan, Hunan, Henan and other provinces will definitely formulate their own Internet action plans. More than 20 provincial local governments across the country have signed strategic cooperation agreements with major Internet companies to carry out comprehensive and in-depth cooperation in cloud computing, big data, smart city construction, Internet public services, e-commerce and Internet finance.
"internet plus" related forums and conferences are getting more and more popular. From government to enterprises to individuals, people are exploring how to use the power of the Internet to achieve efficiency improvement, industrial upgrading and innovation and entrepreneurship. Internet plus Finance, inclusive finance in the Internet Age; Retail in internet plus, achieving e-commerce; Internet+education to achieve universal online education; Internet plus Life Service, Achieving O2O. The "mass entrepreneurship and innovation" promoted by the Internet are also concentrated in these areas. The future Internet will be combined with agriculture, education, medical care, finance, transportation, tourism, culture, home, life service, media, advertising, retail and other industries to form a new ecological landscape.
2. Accelerate the pace of becoming a network power and actively participate in global Internet governance.
In October, the "Thirteenth Five-Year Plan" proposal adopted by the Fifth Plenary Session of the 18th CPC Central Committee clearly stated: "Implement the strategy of strengthening the country by network and accelerate the construction of a new generation of information infrastructure with high speed, mobility, security and ubiquity". China has nearly 700 million netizens, more than 4 million websites, 1.3 billion mobile phone users, 600 million WeChat and Weibo users, and the market value of 7.85 trillion Internet listed companies. It is a veritable Internet power. At present, four listed companies, Alibaba, Tencent, Baidu and JD.COM, have entered the top 10 global Internet companies. Non-listed companies such as Huawei, Ant Financial and Xiaomi have also entered the top 20 in the world. China’s Internet industry is developing steadily, the market competition is full, and its independent innovation ability is enhanced, and it is making great strides to become a network power.
In 2015, China actively participated in the global Internet development and governance, fully expressed China’s proposition of establishing a new global cyberspace order, and put forward the "China Plan" for Internet development and governance. In September, the Chairman of the Supreme Leader visited the United States, and the two sides reached important consensus on cybersecurity and other aspects, and reached six achievements in the Internet field. In December, China hosted the second world internet conference with higher specifications and larger scale. In the keynote speech of the conference, the supreme leader put forward four principles of respecting network sovereignty, maintaining peace and security, promoting open cooperation, and building a well-ordered global Internet governance system, and five propositions of jointly building a community of cyberspace destiny, which have far-reaching influence.
3. Comprehensively promote the national big data strategy and build a data power.
The 13th Five-Year Plan proposes that China will implement the strategy of strengthening the country through network, the "internet plus" action plan and the national big data strategy. In September, the State Council officially issued the "Action Program for Promoting Big Data Development", which put forward the top-level design of China’s big data development from the overall height of the national big data development strategy. The Ministry of Industry and Information Technology is formulating the "Thirteenth Five-Year Development Plan for Big Data Industry". On November 17, People’s Daily published an article signed by Meng Jianzhu, Minister of Public Security, proposing to co-ordinate the construction of infrastructure such as big data, cloud computing center and Internet of Things.
The convergence of the Internet and human economic and social activities has triggered explosive growth of data. Big data has become the core theme of deepening the development of national informatization and the next starting point for the country to promote the development of informatization. Developing big data has become an inevitable choice for building a data power and promoting big data to govern the country. Local governments have begun to actively seize the opportunity to promote the development of big data. On April 14th, Guiyang Big Data Exchange, the first big data exchange in China, was officially put into operation and completed the first batch of big data transactions. The Southern Data Center of the three major communication operators and the first national comprehensive experimental zone for big data were also completed in Guizhou. On December 12th, Zhongguancun in Beijing released the roadmap and enterprise distribution map of "Big Data" industry to the society for the first time. By 2020, Zhongguancun will gather 600 big data innovative enterprises and cultivate 6,000 enterprises with big data application capabilities.
(B) the level of industry development
1. "internet plus" is more manifested as "moving internet plus".
No matter from the market, equipment, traffic, or from the user’s point of view, the mobile Internet will continue to maintain rapid growth. According to CNNIC statistics, as of June 2015, the number of Internet users in China reached 668 million, while the number of mobile phone users reached 594 million. The proportion of Internet users using mobile phones increased from 85.8% in December 2014 to 88.9%. According to the statistics of iResearch, in the third quarter of 2015, the scale of China’s network economy reached 278.39 billion yuan, with a mobile contribution rate of 36.0%, which is still increasing. In October, the monthly average mobile Internet access traffic reached 361.6M, up 88.3% year-on-year, and the mobile Internet access traffic reached 2.88 billion g, which doubled in October. China has built the world’s largest fourth-generation mobile communication (4G) network.
"internet plus" is more manifested as "Mobile internet plus", and its new products, new applications and new models emerge one after another, laying a solid foundation and creating a broad space for "internet plus" action. In the field of the combination of the Internet and traditional industries, the mobile Internet has seized the limelight, and the investment and financing in the fields of transportation, finance, education, medical care, socialization, tourism, entertainment, life service, e-commerce, advertising and marketing are extremely active. A new round of hardware innovation represented by wearable devices, smart cars and smart homes has flourished, with core chips, operating systems, HTML5, 4G/5G, cloud computing and smart homes.
2. Internet services are vertical and refined, and O2O is reshuffled and adjusted.
Various service fields of the Internet are developing vertically, splitting out more subdivided demands, attracting capital investment and giving birth to entrepreneurial opportunities. Among them, O2O field is the most active, covering almost all peripheral services such as automobiles, tourism, education, take-away, laundry, car washing and housekeeping. With the increase of market competitors, the vertical market is characterized by severe verticalization and refinement, and the adjustment of O2O industry is also in full swing.
Driven by capital and market, the core areas of Internet vertical services, such as online reading, O2O, online travel, and dating networks, began to be strong and strong, and the stronger they became. In January, Shanda Literature and Tencent Literature merged; Didi, quick merger in February; In April, 58 Tongcheng and Jiji.com announced the merger; In October, the public comment, the US Mission announced the merger, Ctrip and Qunar announced the merger; In December, jiayuan and Lily.com announced the merger. There are fewer opportunities left for small and medium-sized entrepreneurs in the whole vertical field, but small and beautiful enterprises are still likely to counterattack by deeply cultivating "the refinement of serving people" and "the uniqueness of consumption scenes".
3. The Internet helps the sharing economy to reconstruct a new format and become a new driving force for future industrial development.
On October 29th, the word "sharing economy" appeared in the communiqué of the Fifth Plenary Session of the 18th CPC Central Committee, and it was proposed to "develop the sharing economy". At the second world internet conference, the Chairman of the Supreme Leader talked about the need to focus on developing new formats such as sharing economy during the 13th Five-Year Plan period. It is the development of Internet technology that makes the sharing economy enter a new stage of development. It is suggested that 2015 is the first year of sharing economy in China.
Sharing economy is a sharp weapon to transform and upgrade traditional industries with Internet thinking. The traditional "rules of the game" in the fields of house leasing, transportation, housekeeping, hotels, restaurants and so on are being changed. Apps such as Didi Chuche, Ride, Dada, Everyone Express, and Going Home for Dinner are typical business products of the sharing economy. The sharing economy is changing the industrial chain structure of the format and reconstructing the original format. This format connects many idle, scattered and silent resources in society, and optimizes the allocation of social resources with the help of mobile Internet, big data and geographical location services, which not only reduces the cost, but also solves the "pain point", to some extent, changes the mode of relying on continuous investment to expand reproduction, and finally breaks the original business rules. The new format and mode of sharing economy are becoming a new driving force to promote the future industrial development.
4. The new network culture is booming, creating a new path for the prosperity and development of the cultural industry.
On October 19th, the Central Committee of the Communist Party of China’s Opinions on Prospering and Developing Socialist Literature and Art put forward that we should vigorously develop online literature and art. Driven by the policy and cultural consumption demand, the emerging network culture is booming. At present, the scale of China’s network culture industry reaches 150 billion yuan, up 200% year-on-year; Online original literary works exceed the sum of works published by paper media in contemporary literature for 50 years. With the rapid and extensive coverage of social media, a number of self-media with the responsibility of spreading knowledge of Chinese studies and promoting traditional culture have sprung up. With the help of the Internet, the overseas spread of China culture has reached an unprecedented breadth.
Internet "IP" (the abbreviation of intellectual property, meaning intellectual property) became the top hot word in the Internet field in 2015. The popular IP derived from online literature became the focus of crazy competition among major film and television companies, and many TV dramas adapted from the Internet "IP" were broadcasted, which triggered many rounds of social debates and highlighted the value of online IP. At present, around the popular "IP", a mature one-stop industry such as film and television drama, online drama, radio drama, comics and game production has been formed. From copyright trading to the production and distribution of film and television content, to the development of a series of derivative products such as games, e-commerce, real entertainment, toys, artists’ brokers, fan economy, etc., the improvement of production and creative ability brings about the feasibility of realizing products in various forms. Network culture has become an important force to promote the rapid development of China’s cultural industry.
5. The independent innovation capability of Internet technology has been enhanced to promote the development of smart industry in China.
In 2015, the development of Internet technology in China achieved major breakthroughs in many fields, such as 4G/5G network technology, mobile chips, intelligent terminals, cloud computing, big data, satellite navigation, etc., showing the characteristics of significantly enhancing the independent innovation capability of network technology, accelerating the catching-up of intelligent terminal manufacturing industry, and constantly cultivating new technologies and applications to form new formats.
At the second world internet conference "Light of the Internet" Expo, the virtual fitting mirrors of Baidu unmanned vehicle, Alibaba Cloud technology, JD.COM "Weilian Smart Home" and Suning "Augmented Reality" displayed the latest technologies, products and applications of the Internet in China. Emerging technologies such as the Internet of Things, virtual reality, smart wearables, drones, service robots, and intelligent networked cars accelerate commercialization. The close combination of Internet and intelligent manufacturing has become the leading mode for the development of Industry 4.0 and smart industry. Traditional manufacturing fields are focusing on creating intelligent factories and interconnected factories, developing intelligent manufacturing equipment, developing intelligent terminal products, encouraging artificial intelligence hardware innovation, and promoting digital and intelligent upgrading of consumer electronics products.
6. Internet and industry are deeply integrated to promote the evolution of new media and communication methods.
In 2015, the pace of traditional media in building new media and promoting media integration was greatly accelerated. A "central kitchen" and a "super editorial department" were set up to carry out process reengineering and institutional reorganization, build a media-integrated cloud platform, open up PCs and mobile terminals, and distribute information around users on demand. Drone news, data news and robot news began to appear. Traditional media in many places launched a new version of the news client, and the People’s Daily client was launched in the third phase. Boundless, Southern Plus, Nine Schools, Cover, Meeting Point, Looking at Chutian and Frontier appeared one after another, and the mobile internet field became the main battlefield for media integration and development. In the future, the development of new technologies such as 4G and 5G mobile communication technology, big data, Internet of Things and wearable smart devices will have a far-reaching impact on the transformation of the media industry. Different channels and forms of media information will be integrated into the digital platform. Internet has eliminated the boundary between media and non-media platforms, and new media groups and modern communication systems with three-dimensional diversity and integrated development are taking shape and developing.
(C) the level of social management
1. The construction of the rule of law in cyberspace has been comprehensively promoted, providing a solid guarantee for the network power.
Cyberspace, like the real society, should not only advocate freedom, but also maintain order. Cyberspace is not an "extra-legal place", which has become a social consensus. Promulgating network security laws and regulations and a series of guiding opinions on industry development, strengthening the governance of cyberspace and cracking down on illegal crimes are the proper meaning of cyberspace governance and the necessary guarantee for building a network power.
Since the 18th National Congress of the Communist Party of China, China’s cyberspace legal system has taken shape, covering many aspects, such as cybersecurity legislation, Internet infrastructure and basic resources legislation, Internet service legislation, e-government legislation, e-commerce legislation and Internet criminal legislation. In July 2015, the "Cyber Security Law" (draft) was open to the public for comments. The Ninth Amendment to the Criminal Law of People’s Republic of China (PRC), which was implemented in November, strengthened the protection of citizens’ personal information and added provisions on the crime of fabricating and disseminating false information. The Telecommunications Law and the Electronic Commerce Law are being drafted. In addition, the promulgation of normative documents and opinions such as Several Opinions on Strengthening the Service and Supervision of Market Subjects by Using Big Data, Action Plan for Promoting the Development of Big Data and Opinions on Strengthening the Supervision of Online Markets has become a supplement to cyberspace regulations.
2. Internet thinking promotes the transformation of government functions and innovates social management.
The development of the Internet should benefit people’s lives and be implemented by the transformation of government functions. In May, the State Council issued the Work Plan for Promoting the Combination of Decentralization, Administration and Transformation of Government Functions in 2015, pointing out that in promoting the innovation of supervision methods and optimizing government services, we should actively use information technology such as big data, cloud computing and Internet of Things to explore a new model of "internet plus supervision". In July, the State Council issued the Guiding Opinions on Actively Promoting the "internet plus" Action, clearly requiring "to build an integrated online public service system for the public and a new model of networked social management service with public participation". The Internet is deeply integrated with the government public service system, which simplifies the public service process with Internet thinking, promotes the equalization of resources, and greatly improves the service level and efficiency of the government. Government websites, Weibo, WeChat and government clients are becoming platforms for providing more convenient, better, all-round and all-weather public services.
At the same time, communications, news, radio and television, finance, retail, transportation and other industries have ushered in great changes in the Internet age. In particular, the transformation of traditional industries inspired by the integration of Internet thinking and sharing economy has brought great challenges to government management. On November 23rd, the State Council issued the Guiding Opinions on Giving Full Play to the Leading Role of New Consumption and Accelerating the Cultivation of New Supply and New Motive Force, proposing to adjust and improve the supporting system conducive to the growth of sharing economic model. Making full use of various channels such as trade associations, enterprises and social organizations to build a new governance model with extensive social participation has become a new idea for innovative social management.
Prospect of Internet Development in China in 2016
It should be noted that the development of things is always one after another and affects each other. In 2016, the influence of established Internet-related development plans, policies and regulations will gradually emerge, and new technologies, formats and models of the Internet will continue to develop. The signs and trends that have already appeared in the Internet market will become clearer. In 2016, China’s Internet development may have the following trends that deserve attention:
1. The Internet extends to the "last mile" and is increasingly becoming the infrastructure for economic and social development.
At present, there are nearly 700 million netizens in China, and the number of fixed broadband access ports reaches 407 million, covering all cities, towns and 93.5% administrative villages in China. With the implementation of the "Broadband China" strategy, it is expected to open up the "last mile" of network infrastructure, reduce the gap of Internet development level between the east and the west and between urban and rural areas, further improve the performance of China’s Internet, reduce network charges, make the achievements of Internet development benefit 1.3 billion people in China, and make the Internet truly become the infrastructure of China’s economic and social development, just like air, land, water and electricity. The information transmission, material exchange, management and even people’s way of thinking in society generally rely on the Internet, and the information society is getting closer and closer to us.
2. "internet plus" connects 360 lines, and the intelligent upgrade is accelerated.
Internet technology represented by big data and the Internet of Things is rapidly permeating the whole industry, and the era of wisdom is quietly coming. The development of Internet will promote the intelligent level of products, equipment, production, management and services in manufacturing industry, and further realize product personalization, customization and batch production, process virtualization, factory intelligence and logistics intelligence. The combination of Internet and traditional industries, on the basis of vertical and refined development, will further carry out intelligent upgrading and transformation, and may achieve breakthrough expansion in the fields of car networking, smart home, wearable devices and machine automation. The supervision and service of government departments will also be more "timely, accurate, efficient and intelligent".
3. Network culture has become a new hot spot for investment, and industrial development promotes cultural prosperity.
In 2015, innovations in cultural concepts, contents, formats and communication channels were more reflected on the Internet. Unconsciously, a group of self-media whose mission is to spread the knowledge of Chinese studies and promote traditional culture have been frequently concerned, attracting a large number of fans; The box office of Chinese movies exceeded 40 billion yuan for the first time, and there have been many successful cases of marketing and publicity in third-and fourth-tier cities through internet channels. Some people say that "small town youth" determines the increase of Chinese movie box office; The "internet plus Culture+Finance" model is highly praised for its combination of investment and financial management, art collection and cultural communication. More and more foreign public get the image perception of China through social networks … The increasingly rich material will inevitably lead to higher spiritual pursuit, and internet plus culture will surely become a hot spot for investment. Some Internet companies have begun to set foot in media, film and television and other cultural industries.
The consumption of Internet cultural products will become a huge market. It will become a trend to promote the effective integration of cultural industry content and channels through the Internet, promote the combination of cultural creativity with the real economy and financial capital, and realize the extension and appreciation of the value of the whole industrial chain. Taking the network as a platform to promote the sharing of cultural achievements and taking culture as a carrier to promote the construction of a community of destiny in cyberspace will become the consensus of cultural inheritance and cultural innovation in the Internet age.
4. Technological innovation, industrial development and space governance to jointly promote the construction of a network power.
There is still a big gap between China and developed countries in terms of infrastructure, technology, industry, network security and network discourse right. Only by breaking the weakness of core technologies such as PC and mobile phone operating system and realizing the leap from consumer Internet to internet plus industry can we promote the development of network economy and network culture and make due contributions to the prosperity of China’s economy and culture.
At the same time, ensuring network security, promoting orderly development and building an Internet governance system will be the theme of China Internet in the future. The concept of interconnection, sharing and co-governance, which originated in China, will spread more widely around the world. More and more Internet enterprises in China will go to the world and drive the development of the Internet all over the world through their own development. China will play a more active role in the development and governance of the Internet, and the pace of becoming a network power will become more and more solid.
Ten years after its establishment, Flash plans to go public in the United States.
According to the official website of the US Securities and Exchange Commission (SEC), on September 13th, BingExLimited (stock code: "FLX") submitted a prospectus to be listed on NASDAQ, with China International Finance Corporation, CLSA, Deutsche Bank and UBS Investment Bank as underwriters.
Since its commercial operation in 2014, as of June 30, 2024, Flash Transport has about 2.7 million registered riders, and its service coverage has expanded to 295 cities in China.
According to the data of the third party iResearch, according to the revenue in 2023, Flash Delivery is the largest independent express delivery service provider in China, with a market share of about 33.9%. According to the prospectus, unit economic benefit and replicable network are the core competitive advantages of Flash, which enables the company to continuously expand its scale and order volume and improve its profitability.
Xue Peng, the founder of Flash, is a veteran in the logistics industry. He has been the CEO since the establishment of the company and has been a director since May 2014. Before the establishment of Flash Delivery, China Express Logistics Integrated Service Platform Easy Post was established and developed. Yu Hongjian, co-founder, director and CEO of Flash, is Xue Peng’s old partner. He worked with Xue Peng for many years before he founded Flash.
According to the prospectus, before the IPO, Xue Peng held 22.7% equity and 74.6% voting rights; Yu Hongjian holds 1.6% equity and 0.5% voting rights. Among institutional shareholders, SIG, CDH Venture Capital and Shun Wei Capital hold 9.7%, 8.9% and 7.8% respectively. They have 3.2%, 2.9% and 2.6% voting rights respectively.
According to Tianyancha, Flash has gone through more than ten rounds of financing since its establishment ten years ago. The latest round of financing was completed in 2021. According to the prospectus, in March, April and May of 2021, Flash received 747.8 million yuan from the D-2 round of financing.
In 2023, it turned losses into profits, and the annual gross profit margin increased year by year, but it was less than 10%.
As a one-to-one express delivery platform in the instant delivery industry in the same city, Flash delivery is a pioneer in the instant delivery industry in the same city, providing various exclusive services for different types of delivery for customers, and the share of Flash delivery is the largest according to the revenue in 2023.
Compared with other real-time delivery platforms, flash delivery once said that its biggest feature is focusing on "one-to-one express delivery", which means that a flash operator is responsible for the whole service process from picking up items from the sender to delivering them to the recipient, and a flash operator can only take one order at a time, and will not take other orders until the current order ends. For this reason, many users tend to choose more respectful exclusive services when faced with the delivery needs of important items such as gifts.
According to the prospectus, it is estimated that from 2023 to 2028, the independent on-demand express delivery market in China will grow at a compound annual growth rate of 27.8%, exceeding the compound annual growth rate of 19.1% of the overall on-demand delivery market in China. By 2028, the overall on-demand distribution market in China will increase to 809.6 billion yuan, and the independent on-demand express delivery market in China will increase to 53.237 billion yuan.
However, at present, the competition in the instant delivery industry in the same city is fierce, and SF Express in the same city, Meituan Delivery in the takeaway department and Dada Group in the e-commerce department are all accelerating to seize the market.
Dada Group (Nasdaq: DADA) was listed on NASDAQ Exchange on June 5, 2020. SF City (9699.HK) was listed on the Hong Kong Stock Exchange in December 2021. Among them, the "first instant retail share" Dada Group has not yet achieved profitability. As the largest third-party instant delivery service in China, Shunfeng Tongcheng started to exert its strength. In 2023, its revenue reached 12.4 billion yuan, an increase of over 20%, and it achieved full-year profit for the first time. In the first half of this year, the income was nearly 6.88 billion yuan, a year-on-year increase of 19.6%; The net profit attributable to the owners of the company reached a record high of about 62.17 million yuan, up 105.1% year-on-year. It is worth noting that after landing in the capital market, the share price of Dada Group has fallen by over 90% compared with the issue price, and the share price of Shunfeng City has fallen by over 30%.
The prospectus shows that the flash has achieved profitability in 2023. The increase in customer demand has promoted higher order volume, and the growing number of riders has enhanced network density and delivery capacity, which has brought about organic growth in customer base and order volume.
Specifically, in the past three years, the revenue of flash delivery was 3.04 billion yuan, 4.003 billion yuan and 4.529 billion yuan respectively, of which 2022 and 2023 increased by 31.6% and 13.1% respectively. In the first half of this year, the revenue from flash transmission was 2.285 billion yuan, a year-on-year increase of 7.6%.
In the past three years, the net profit was-291 million yuan,-180 million yuan and 110.5 million yuan respectively, of which the year-on-year loss was reduced by 38.1% in 2022, and it turned losses into profits in 2023. In the first half of this year, the net profit was 123.7 million yuan, a year-on-year increase of nearly two times. In 2023, the net profit rate was 2.4% and the net loss rate was 4.5%. The net profit rate in the first half of this year was 5.4%, compared with 2% in the same period last year.
The prospectus pointed out that the realization of profit in 2023 was mainly due to the increase in government subsidies determined by relevant government departments as appropriate.
In the past three years, the gross profit margin has increased year by year, 6.2%, 6.5% and 8.7% respectively. The gross profit margin in the first half of this year was 11.3%, compared with 8.6% in the same period last year.
The average charge for flash delivery is 16.5 yuan per order: the income is declining year by year, which is obviously higher than that of peers.
According to the prospectus, all the income from flash delivery comes from the fees charged for providing on-demand express delivery services to customers. Flash delivery provides a unified pricing model, and the floating rate of each order is calculated according to the formulas of city, delivery distance, package weight and volume, and night surcharge. If the supply is insufficient due to bad weather or other reasons, the "peak price" may be adopted.
According to reports, the flash network mainly recruits riders through crowdsourcing mode, most of them are crowdsourcing individuals, and a small number of them are recruited from outsourcing distribution agencies in a few cities. After back training, riders become flash riders. According to the prospectus, with high-value services and crowdsourcing mode, we can maintain the light asset business model, reduce fixed costs and maintain high scalability, and quickly enter more cities.
Specifically, the number of registered flash riders increased from about 1.1 million in early 2021 to about 2.7 million on June 30, 2024. The number of registered customers increased from about 31.1 million in early 2021 to about 88.9 million on June 30, 2024. In addition, the number of daily orders for each active rider increased from 7.2 orders in 2021 to 8 orders in 2022, and further increased to 8.8 orders in 2023 and 9.3 orders in the six months to June 30, 2024.
In the past three years, the number of flash orders was 158.6 million, 213.4 million and 270.7 million. In the first half of this year, 138.1 million orders were completed. The corresponding income is 3.04 billion yuan, 4.003 billion yuan, 4.529 billion yuan and 2.285 billion yuan respectively. Based on this calculation, the average income of a single order in the past three years and the first half of this year was 19.2 yuan, 18.8 yuan, 16.7 yuan and 16.5 yuan respectively, showing a downward trend year by year.
It is worth noting that the prospectus quoted the data of the third party iResearch, showing that within six months as of June 30, 2024, Flash delivery can charge a fee at an average price of 16.5 yuan per order, which is significantly higher than that charged by other major participants in the on-demand distribution industry.
However, in terms of risk factors, the prospectus mentioned that although Flash does not intend to compete with aggressive pricing policies that are not conducive to long-term growth, it cannot guarantee that it will not be forced to lower the delivery price of customers, increase the customer incentives we provide or increase our marketing and other expenses to attract and retain customers due to competition, supervision or other reasons, in order to cope with the competitive pressure.
In addition, the salary and reward paid to "Flash Ride" are the largest components of the income cost, accounting for 90.5%, 90.3% and 87.8% of the total income in the past three years, 85.4% in the first half of this year and 87.9% in the same period last year. According to the prospectus, this shows that even in the rapid expansion stage, flash delivery can maintain a stable cost structure in the same period.
As for the growth strategy, the prospectus points out that it plans to continue to expand market share, broaden service scope and application scenarios, strengthen market-leading brand image and invest in advanced and innovative technologies. According to the prospectus, the flash delivery plan improves the penetration rate of the existing market through differentiated distribution services. At present, flashover is still in the early stage of covering the target market, and the geographical coverage of flashover will be extended to more cities in China in the near future. In addition, it plans to use its highly scalable business to expand service products to cover more application scenarios.
Pulmonary nodule has become a high-frequency word on the physical examination list. People pay attention to pulmonary nodules, even to the point of panic, all because part of the nodules is early lung cancer. Especially when the word "ground glass" appears in the inspection report, the patient is more anxious and thinks that the difference is cancer.
Chen Liang, director of the Department of Thoracic Surgery of jiangsu province hospital (the First Affiliated Hospital of Nanjing Medical University), told the reporter that with the increase of cases, the medical consensus on pulmonary nodules is constantly being updated. Now the ground-glass nodules have been classified into the "relative safety zone". As long as the word "ground glass" appears, the nodules are inert, so patients need not be afraid, just follow up regularly. In this big coffee health class, let’s learn more about pulmonary nodules!
With the word "ground glass", nodules are inert.
"Many lung cancers are developed from ground glass nodules!" "Be careful when there are solid components in ground glass nodules, and the malignant probability of semi-ground and semi-solid nodules is the highest!" — — This is the main point that will be mentioned in many popular science of pulmonary nodules before. If there is a "ground glass nodule" on the physical examination list, the fear of patients with pulmonary nodules will escalate. Director Chen Liang told Yangzi Evening News/Zi Niu News reporter that this concept needs to be updated. There are ground glass nodules, but it is relatively safe.
Director Chen Liang explained that infectious diseases such as tuberculosis and fungal infection and chronic inflammation may produce nodules on the lungs. Ground-glass nodules are flaky blurred shadows that we can see on chest CT, just like ground glass. Ground glass nodules are divided into "pure grinding" and "mixed grinding". The diameter of pure ground glass nodules within two centimeters in the international guidelines can be followed up; There are ground glass components and some solid components in the "mixed grinding". The guidelines for this kind of nodules also stipulate that: if the diameter is less than 6 mm, there is no need for follow-up or annual follow-up; 6-8 mm, it is recommended to follow up once every 6-12 months; Those larger than 8 mm are followed up every 3-6 months.
The observation and summary of pulmonary nodules in medicine are also updated. The consensus now is that even if it is already an invasive adenocarcinoma, as long as there is ground glass, it is a low-grade malignant and inert tumor, and the surgical prognosis is excellent.
Don’t intervene too early, even minimally invasive surgery is invasive.
Director Chen Liang said that such patients are often encountered in outpatient clinics. This hospital found nodules by filming and quickly went to a large hospital for enhanced CT or even PET-CT；. Some patients will give an example, "Some people around me have nodules smaller than me, and they are all malignant", so they strongly demand surgery. There will also be patients with three or four millimeters of nodule reports coming from other places to "seek an answer".
Patients often want big experts to determine whether their nodules are cancer. "But the eyes of experts are not microscopes, and sometimes they can’t completely determine whether they are benign or malignant." Director Chen Liang said, is it possible that two or three millimeters of nodules are malignant or have malignant "potential"? It’s a small chance, but it’s possible, but is it wrong for the doctor not to operate? Not really. When a doctor watches a film, what he really needs to grasp is the opportunity of intervention, so as to make the patient benefit the most.
Small nodules of 3-4 mm, some hospitals and doctors may also advise patients to operate, which is actually overtreatment. Minimally invasive surgery is also invasive, and there will be injuries. It is definitely not the optimal solution to let patients who could have been "calm" for several years, more than ten years, or even without intervention for life, bear surgical injuries and various risks prematurely.
Director Chen Liang, for example, said that the patients with pulmonary nodules who were followed up in his hand were suspected to be carcinoma in situ. After 12 years of observation, it was confirmed that they were still carcinoma in situ after surgery. "Atypical hyperplasia, cancer in situ, now think they are precancerous lesions, not cancer. From carcinoma in situ to minimally invasive carcinoma, it seems to be ‘ Advanced ’ In fact, they are only 1-2 mm apart, and the progress is very slow. Many patients are followed up for 5-10 years, and grasping the indications and timely surgery will not affect their health. " Director Chen Liang said that they spend the most time in outpatient clinics, but instead advise patients not to worry, and they can afford to wait.
Big coffee biography
Chen Liang, director of thoracic surgery department of the First Affiliated Hospital of Nanjing Medical University, chairman of the thoracic surgery branch of Jiangsu Medical Association, and president-designate of the thoracic surgeon branch of Jiangsu Medical Association. Committed to the surgical treatment of early lung cancer, he is good at the diagnosis and treatment of thoracic surgery-related diseases, especially lung segments. He has completed more than 1,500 cases of thoracoscopic anatomical pneumonectomy, including more than 500 cases of segmental pneumonectomy and subsegmental pneumonectomy. Thoracoscopic subsegmental pneumonectomy was reported for the first time in the world, which was widely recognized by people in the industry. He has performed surgical demonstrations at conferences at home and abroad for many times, and his technology has spread throughout the country and even abroad. Successfully performed the world’s first mixed reality (MR) assisted lung tumor resection; In China, the concept of "accurate pneumonectomy under the guidance of 3D-CTBA" was first put forward, and the first 3D-CTBA reconstruction system, DeepInsight, was developed in cooperation with Neusoft Company, and the software was successfully copyrighted, which has been widely used in China, including Taiwan Province. He has made many special reports and surgical demonstrations at international and domestic thoracic surgery conferences, and is committed to promoting accurate thoracoscopic pneumonectomy.
He presided over the compilation of the first Atlas of Thoracoscopic Anatomical Segmental Pulmonary Resection in China and the first Atlas of Endoscopic Anatomical Segmental Pulmonary Resection in the world.
The image is hanging in the air, and it can be seen synchronously 30 kilometers away from here.
What kind of nodule needs surgery? Director Chen Liang said that there are "standards" in domestic and foreign guidelines at present. Generally speaking, surgery will only be considered if it is greater than 8 mm. If the nodule is suspected to be carcinoma in situ, micro-invasive carcinoma, or the size, shape and density of the nodule change, follow-up or elective surgery can be selected. If the nodule is located at the periphery of the lung, it is easier to handle, and local resection can be used, with little damage to the lung; If the position is deep, the pulmonary vessels and bronchi may be damaged during the "forced" resection, resulting in postoperative hemoptysis, limited lung expansion and other complications. "At present, minimally invasive surgery has been able to achieve anatomical lung resection, that is, to dissect a lung segment from the lung lobe, while ensuring the margin and minimizing the damage." Jiangsu province hospital is one of the earliest hospitals in China to carry out pneumonectomy, and has trained many domestic thoracic surgeons. The "Anatomical pneumonectomy course" of thoracic surgery has just passed the final certification of the Royal College of Surgeons, and it is also the first training course of pneumonectomy in the world.
In 2017, jiangsu province hospital Thoracic Surgery completed the world’s first thoracoscopic segmental resection of early lung cancer assisted by mixed reality (MR) technology. In 2019, with the help of 5G technology, the first international 5G+MR remote real-time combined segmental pneumonectomy was completed. Under MR technology, after the doctor wears special glasses, the lung image data is "dragged" from the computer screen through artificial intelligence three-dimensional reconstruction, suspended in the air and shared in real time. Director Chen Liang, who is in the hospital headquarters, can mark the image remotely with voice and marker pen, and every instruction detail will appear clearly and without delay in the operating field of the surgeon in the operating room of Pukou Branch, 30 kilometers away. With the support of new technology, the treatment of pulmonary nodules can be more and more minimally invasive and accurate, and difficult remote surgery has also become possible.
See the real pulmonary nodules from the numbers.
Director Chen Liang said that jiangsu province hospital Thoracic Surgery conducted a cohort study of lung cancer in the physical examination center of the hospital. From May 2019 to 2020 (except January-March of the COVID-19 epidemic), a total of 10,225 cases were examined by CT, of which the nodule detection rate was 74.1%, and lung cancer confirmed by pathology accounted for three thousandths of the total number of people examined. It can be seen from this data that the proportion of cancer in pulmonary nodules is still not high.
At the same time, the number of pulmonary nodule operations in jiangsu province hospital was 1,836 in 2016 and 4,393 in 2020, an increase of 139% in five years. At present, the malignant rate of surgical patients is more than 90%.
The increase of pulmonary nodule cases is mainly related to the increase of incidence, the increase of detection rate after the improvement of imaging examination accuracy and the early diagnosis.
What new car can I buy for 70,000-90,000 yuan? In the era of fuel vehicles, we blurted out "Honda, Volkswagen and Toyota to dazzle" three musketeers. In the era of new energy vehicles, BYD directly penetrated the industry threshold at a price of 73,800-89,800 yuan. In the field of small hatchback, BYD Seagull can be regarded as a pure electric flat replacement model of Honda Fit. Although BYD Seagull is positioned as a large-sized micro electric vehicle (close to the size wheelbase of a small car), its interior space performance is close to that of Honda Fit and Volkswagen Polo due to its unique body structure and power layout based on BYD e platform 3.0.
Today, the team leader commented on the 2023 BYD Seagull Free Edition, which is a mid-range model of Seagull. There is no discount at the terminal, and the guide price is 78,800 yuan.
Model: BYD Seagull Free Edition.
Guide price (i.e. bare car price): 78,800 yuan.
The length of the vehicle is 3780mm/ the wheelbase is 2500mm/ the single motor is 75hp /CLTC has a battery life of 305km.
[Satisfied]
The appearance is relatively neutral, and the body structure presents a quite good sense of movement. Because the weight of the vehicle is small and it is an electric vehicle, its dynamic response is fast, the shift is completely without setbacks, the acceleration is very linear, the start is very silky, and there is no noise from the engine, so its quietness has a natural advantage. In addition, the interior materials of this car are also excellent, equipped with leather steering wheel and leather sports style seats, as well as 7-inch full LCD instrument and 10.1-inch central control panel. In this price level, this free version of Seagull is richer and safer than the joint venture car. Seagull comes standard with 4 airbags and front and rear penetrating side air curtains, ESP electronic vehicle stability system, EPB electronic parking, reversing image, cruise control, and the free version is equipped with 16-inch aluminum alloy wheels, ultrasonic radar, satellite navigation, keyless start/entry, external discharge and other equipment functions.
[dissatisfied]
Seagull’s chassis has a general texture and a certain degree of comfort, which is suitable for driving on urban roads. It runs on unpaved roads, and small bumps are not well filtered out. The trunk space is a little small, which is equivalent to sacrificing the trunk for the back row space, and the trunk is not high enough to put much things. Finally, the interior of the new car stage smells very bad, because there are many plastic materials, and there will be a choking smell after exposure.
[Power consumption]
At present, the power consumption per 100 kilometers of this car is 13kWh, because it needs to turn on air conditioning and refrigeration in summer, and the battery life is discounted, basically around 200 kilometers.
[Driving experience]
Seagull is a particularly easy-to-operate vehicle. One is that it is small in size and it is not difficult to drive. Then it has a fast starting speed, light and easy steering and sensitive braking, which is quite suitable for novice drivers and girls. However, it should be noted that after the car starts running, it is necessary to control the turning range, and the roll angle of the car is limited.
[Summary]
BYD Seagull can well replace Honda Fit and Volkswagen Polo, after all, the price is less than 80,000 yuan. It has smooth acceleration performance and quiet driving/riding environment, and it is relatively easy to drive. It only relies on electric power to drive, which is equivalent to saving fuel and money. The cost of using a car is very low, and it costs several yuan for driving 100 kilometers. Generally speaking, this car is very suitable for buying vegetables and taking children to and from school.
